He rose highest to flick the ball on to Christopher Nkunku as Maresca's men opened the scoring in the first half, as well as saving Chelsea at the back early on in the game.
Intercepted numerous Southampton passes into midfield and progresses the Blues so well down the left, playing a vital role in Chelsea's second goal doing exactly that.
Probably Chelsea's most creative player in the first half, Enzo played a deeper role than he has the past two games and was arguably robbed of two assists by Cole Palmer.
Marking 6ft 7inch giant Paul Onuachu is no easy feat no matter how good you are, but Chelsea's own Levi Colwill did that job pretty well.
Chelsea's pantomime villain has made the inverted fullback role his own under Enzo Maresca, and is one of the best in the Premier League at doing that job.