Scarlets back Ellis Mee will make his Test debut when Wales begin life after Warren Gatland against Guinness Six Nations title favourites Ireland on Saturday.
That was Gatland’s final match at the helm, with Wales suffering a 14th successive Test defeat and eighth Six Nations reversal in a row.
Gloucester centre Max Llewellyn and fly-half Gareth Anscombe were recalled by Sherratt after Gatland left them out of his Six Nations squad, and go straight into the starting line-up.
The Nottingham-born wing, whose mother is from Newport, is among eight personnel changes made by interim head coach Matt Sherratt following Wales’ 22-15 loss to Italy.