Sky Bet Championship leaders Leeds have decided against surgery for now but boss Daniel Farke says Ampadu will be out for “four to six weeks”, thereby ruling him out of Wales’ opening World Cup qualifiers at home to Kazakhstan on March 22 and in North Macedonia three days later.
Ampadu’s absence will come as a hammer blow to Wales boss Craig Bellamy, who is already set to be without Harry Wilson and Wes Burns through injury next month.
Wales will be without injured Leeds captain Ethan Ampadu for the start of their World Cup qualifying campaign.
The 54-times capped international was injured in September and spent 10 weeks out, missing four of Wales’ six Nations League games.
Ampadu damaged a knee in training earlier this week and scans have now revealed the influential 24-year-old defender or midfielder has suffered a cartilage injury.
