West Ham predicted XI: Fabianski; Wan-Bissaka, Mavropanos, Kilman, Emerson, Alvarez; Summerville, Soucek, Paqueta, Kudus; Bowen.
The Hammers are looking to string together some consistency after responding to their dismal defeat away at Leicester earlier this month with a win and a draw.
Midfielder Carlos Soler has started to impress of late but will be ruled out of the game after picking up a booking to take his tally to five for the season against Bournemouth.
Michail Antonio underwent surgery on a lower limb fracture sustained in a road traffic accident earlier this month.
Still, their task against the Seagulls – who have never actually lost at the London Stadium – has been made all the more difficult following a recent suspension.