Cancer vaccine being created by UK scientists could stop disease up to 20 years early

Cancer vaccine being created by UK scientists could stop disease up to 20 years early

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Cancer vaccine being created by UK scientists could stop disease up to 20 years early
Author: Rachel Clun
Published: Jan, 27 2025 13:02

A new partnership between the University of Oxford and GSK aims to develop vaccines against cancer before develop. Scientists are working to create a new cancer vaccine that could “detect the undetectable” and stop the disease up to 20 years before it has the chance to develop.

 [University of Oxford professor Sarah Blagden, who is director of the partnership, said the research was aimed at finding ways to stop the cancer developing]
Image Credit: The Independent [University of Oxford professor Sarah Blagden, who is director of the partnership, said the research was aimed at finding ways to stop the cancer developing]

Pharmaceutical giant GSK and the University of Oxford have teamed up to make a vaccine that targets cells at the pre-cancerous stage. The university has world-leading expertise in the study of pre-cancer biology, such as through identifying and sequencing neoantigens, which are proteins that forms on cancer cells and can be a target for drugs.

Professor Sarah Blagden, who is director of the partnership, said cancer “does not come from nowhere”. “You always imagine it would take about a year or two years to develop in your body but, in fact, we now know that cancers can take up to 20 years, sometimes even more, to develop - as a normal cell transitions to become cancerous,” prof Blagden told BBC’s Radio 4 on Monday.

“We know that actually at that point, most cancers are invisible when they are going through this, what we now call pre-cancer stage. And so the purpose of the vaccine is not to vaccinate against established cancer, but to actually vaccinate against that pre-cancer stage.”.

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