Cancer vaccine being created by UK scientists could stop disease up to 20 years early
Cancer vaccine being created by UK scientists could stop disease up to 20 years early
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A new partnership between the University of Oxford and GSK aims to develop vaccines against cancer before develop. Scientists are working to create a new cancer vaccine that could “detect the undetectable” and stop the disease up to 20 years before it has the chance to develop.
Pharmaceutical giant GSK and the University of Oxford have teamed up to make a vaccine that targets cells at the pre-cancerous stage. The university has world-leading expertise in the study of pre-cancer biology, such as through identifying and sequencing neoantigens, which are proteins that forms on cancer cells and can be a target for drugs.
Professor Sarah Blagden, who is director of the partnership, said cancer “does not come from nowhere”. “You always imagine it would take about a year or two years to develop in your body but, in fact, we now know that cancers can take up to 20 years, sometimes even more, to develop - as a normal cell transitions to become cancerous,” prof Blagden told BBC’s Radio 4 on Monday.
“We know that actually at that point, most cancers are invisible when they are going through this, what we now call pre-cancer stage. And so the purpose of the vaccine is not to vaccinate against established cancer, but to actually vaccinate against that pre-cancer stage.”.