Scotland: B Kinghorn (Toulouse), K Rowe (Glasgow), H Jones (Glasgow), T Jordan (Glasgow), D Van der Merwe (Edinburgh), F Russell (Bath), B White (Toulon); P Schoeman (Edinburgh), D Cherry (Edinburgh), Z Fagerson (Glasgow), J Gray (Bordeaux), G Gilchrist (Edinburgh), J Ritchie (Edinburgh), R Darge (Glasgow), J Dempsey (Glasgow).
Replacements: E Ashman (Edinburgh), R Sutherland (Glasgow), W Hurd (Leicester), S Skinner (Edinburgh), G Brown (Glasgow), M Fagerson (Glasgow), J Dobie (Glasgow), S McDowall (Glasgow).
England: M Smith (Harlequins); T Freeman (Northampton), O Lawrence (Bath), H Slade (Exeter), O Sleightholme (Northampton); F Smith (Northampton), A Mitchell (Northampton); E Genge (Bristol), L Cowan-Dickie (Sale), W Stuart (Bath), M Itoje (Saracens), O Chessum (Leicester), T Curry (Sale), B Earl (Saracens), T Willis (Saracens).
Replacements: J George (Saracens), F Baxter (Harlequins), J Heyes (Leicester), G Martin (Leicester), C Cunningham-South (Harlequins), B Curry (Sale), H Randall (Bristol), E Daly (Saracens).
There are two changes to the Scottish pack, with the Edinburgh pair Pierre Schoeman and Jamie Ritchie taking over from the Glasgow duo Rory Sutherland and Matt Fagerson in the front row and back row respectively.