And that will be the one that'll hit hardest in that Arsenal boardroom, and with Mikel Arteta, and the dressing room and the players, because they're desperate to win a title and they would have felt like they were inching nearer.
Arsenal have suffered plenty of injuries this season, most notably to star man Bukayo Saka, before Gabriel Jesus and Kai Havertz were ruled out for the rest of the season.
“I know that they've lost Saka, and I know that they've lost Jesus, and I know they've lost Haverts, which are big blows.
The Gunners on Saturday blew the chance to close the gap on table-topping Liverpool to five points by losing at home to West Ham.
Gary Neville believes Arsenal’s “obsession” with set-pieces is contributing to their failure to win the Premier League title this season.