This weekend expect to see Moyes release Harrison with Mykolenko regularly making aggressive runs to stretch the pitch and occupy the right wing-back for United, likely to be one of Diogo Dalot or Patrick Dorgu.
One of the first changes Moyes implemented saw the defensive line shift from a back four to a more fluid structure, with Jake O'Brien coming in at right-back and playing a deeper, more hybrid role.
The in-form Toffees take their new manager bounce into a clash with Moyes' old club Manchester United, whom he originally left Everton in 2013 to manage before he was sacked ten months later.
We have already touched on Moyes changing the basic structure of Everton to get the best out of Iliam Ndiaye on the left side of the pitch.
Despite Harrison having a very different profile to Ndiaye, the role will remain fluid with Harrison coming inside to receive in pockets of space where he can get turned to attack and hurt the opposition with his ball-carrying ability.