It said in a statement, the London Fire brigade said: "Four fire engines and around 25 firefighters have been called to a fire at a hotel and restaurant on Chiltern Street in Marylebone.
Guests of Netflix, including American A listers including Selena Gomez, 32, and Zoe Saldana, 46, are thought to have been staying at the hotel.
Preparations were well underway to host Hollywood royalty at Chiltern Firehouse on Sunday night at the venue - with some of their film talent also staying at the hotel.
On Friday a fire broke out at the historic Chiltern Firehouse hotel and restaurant in London's Marylebone.
After months of preparations and tens of thousands of pounds spent, the A-list bash at Chiltern Firehouse in Central London, now hangs in the balance.
