The versatile defender made limited contact with the ball, bringing the West Ham star down, and after an initial yellow card referee Craig Pawson upgraded it to red following a VAR review.
The Prem explained: "VAR checked the referee’s call of yellow card to Lewis-Skelly for a challenge on Kudus – deeming it denial of an obvious goal-scoring opportunity due to the goalkeeper’s position and there being no covering defender, therefore recommended an on-field review.
ARSENAL ace Myles Lewis-Skelly was sent off once more following another VAR review.
Lewis-Skelly, 18, and the rest of Mikel Arteta's men endured a miserable afternoon at the Emirates as they lost 1-0 to London rivals West Ham following Jarrod Bowen's winner.
That shocking loss dealt a major blow to the Gunners' Premier League title hopes as a victory would have seen them cut down the deficit with leaders Liverpool to five points.