"At his first NATO Ministerial with Allied counterparts, he will engage with NATO Allies and partners to discuss the need to boost Allied defence spending, increase European leadership, and expand defence industrial base capacity on both sides of the Atlantic," the defence department said in an advisory.
Mr Trump has said he believes his NATO allies should be spending at least 5% of national income on their militaries - Sir Keir Starmer's government has yet to say when it expects UK defence spending to inch up to 2.5% from around 2.3%.
At a meeting of NATO's Ukraine Defence Contact Group, Mr Hegseth "will reiterate President Trump's commitment for a diplomatic end to the war in Ukraine as quickly as possible".
US defence secretary Pete Hegseth has posted pictures of himself exercising with American marines in Germany ahead of his first NATO meeting this week.
As well as training with the marines, he is set to visit the US European Command and US Africa Command in Germany to meet senior military leaders.