The London Fire Brigade (LFB) said on Friday evening that 20 fire engines and around 125 firefighters have been called to a blaze on Chiltern Street in Marylebone.
A fire has broken out at the Chiltern Firehouse, leading to around one hundred people being evacuated from the luxury London hotel.
In a statement, the LFB said: “There is a fire in ducting which leads from the ground floor to the roof of the four-storey hotel with a restaurant on the ground floor.
Chiltern Firehouse is known for being frequented by celebrities and was the location of Kylie Minogue’s 50th birthday party in 2018.
It added that officers were first called at 2.52pm and are still at the scene, with the cause of the fire unknown.