The show explored Dave Myers' life following the end of his cancer treatment, and the series ultimately coincided with his death on February 28 after a two-year battle with the illness.
The news was shared by his long-time colleague Si, 58, who told fans of the pair, known collectively as the Hairy Bikers, that he'd been by Dave's side when he died.
It came after Si praised Dave for making the series special after being able to return to filming following treatment for cancer.
The BBC 2 series saw Si King and Dave explore the west coast of the UK after the latter finished his cancer treatment.
On one of the last episodes of The Hairy Bikers Go West, the two explored Lancashire, which had an emotional connection for Dave as he was born in the county.