"Officers were called at 6.32pm yesterday (9 February) to reports of a collision involving a silver Toyota Yaris and two child pedestrians on Ransdale Road, near to the junction of Ramsey Street.
A spokesperson for the force said: "Police are appealing for witnesses after a fatal road traffic collision in Bradford.
"This is the first time we've had a bad accident on this road in the 40 years I've lived here but there have been lots of near misses.
The child was walking home with her 16-year-old sister when they were struck by a silver Toyota Yaris that "came out of nowhere".
Neighbours heard the tragic accident from their homes in Bradford at around 6.30pm on Sunday and hurried outside.