Dragusin, signed from Genoa for £25million in January last year, has made a total of 28 appearances for Ange Postecoglou’s side this season, including 14 Premier League starts.
The loss of Dragusin was the latest in a long injury list for the under-pressure Spurs boss, who has seen his side now exit the Carabao Cup and FA Cup in the space of 72 hours.
Spurs sit 14th in the Premier League ahead of their next game at home to Manchester United on Sunday, with Europe now the sole focus for Postecoglou to deliver a trophy in his second season.
Tottenham defender Radu Dragusin is determined to come back stronger following surgery to repair anterior cruciate ligament damage.
The Romanian sustained a serious knee injury during the Europa League win against Elfsborg on January 30, and is set for a lengthy spell of rehabilitation.
