A Greater Manchester Police spokesperson said: "Emergency services are responding to reports of a collision involving a tram and a van in Manchester city centre.
A North West Ambulance Service spokesperson said: "Our thoughts are with the family and loved ones of the little girl who sadly passed away following an incident in Manchester city centre today.
The tragic tot was walking on Mosley Street, Manchester, just before 10am on Saturday when the van reportedly rebounded off the tram and hit her.
Another shop keeper told The Sun: “It looked like the tram had hit the van to one side.
SHOPKEEPERS told of their horror after a three-year-old girl was killed in a tram crash with a van, as cops continue their hunt for the driver a day later.