Spurs captain Heung-min Son could even be rested this weekend to save him for City, but is more likely to be replaced in the second half, while Mathys Tel is set to continue through the middle in the absence of Dominic Solanke (knee) and Richarlison (calf).
Pape Matar Sarr and Yves Bissouma are also available, however, while Postecoglou could choose to hand Archie Gray, 18, a first start in midfield after his impressive displays while deputising at centre-half.
Tottenham head coach Ange Postecoglou has options to choose from for Saturday's visit to struggling Ipswich and may pick an XI with the mid-week game against Manchester City in mind, too.
James Maddison is likely to keep his place at No.10 after scoring the winner against United, and a pairing of Rodrigo Bentancur and Lucas Bergvall would offer a blend of energy and technical quality alongside the England playmaker.
Predicted Tottenham XI (4-3-3): Vicario; Porro, Danso, Davies, Spence; Bentancur, Bergvall, Maddison; Kulusevski, Son, Tel.