Dejan Kulusevski could also start at No8 or on the right wing, with Postecoglou also needing to decide which of Heung-min Son and Mathys Tel lead the line.
Postecoglou has decisions to make at centre-back and in midfield, with Rodrigo Bentancur, Yves Bissouma, Pape Matar Sarr, Lucas Bergvall and Archie Gray all competing for three positions in the middle of the park for Tottenham.
Micky van de Ven (hamstring), Cristian Romero (thigh), Dominic Solanke (knee), Richarlison (calf) and Radu Dragusin (knee) are all still sidelined.
Gray could also play at the back, although January signing Kevin Danso and Ben Davies seem more likely to get the nod there.
Predicted Tottenham XI (4-3-3): Vicario; Porro, Danso, Davies, Spence; Bentancur, Sarr, Bergvall; Kulusevski, Son, Tel.