The Internet star said: "I think we'll hit a billion subscribers, and I don't think anyone will be anywhere near close, because once you make a couple of million dollars, why would you live the life I live?
"There's a reason no one makes videos like me - like not even close - because no one wants to live the life I live.
He said: "The average person does not want to live the life I live or be in my head.
In addition to the ever-growing YouTube platform, MrBeast now fronts a reality game show on Amazon Prime with 1,000 contestants competing in physical and mental challenges for a cash prize.
Speaking with Steven Bartlett on the Diary of a CEO podcast, he said: "If my mental health was a priority, I 'wouldn't be as successful as I am - and, that's just a sad fact.