Det Insp Richard Stott said: "Concern was raised for the woman last night, and due to the length of time since she was last seen and concerns that she may have come to some harm, we are treating this as a murder investigation.".
COPS have launched a "no body" murder investigation after a woman went missing from a sleepy village several weeks ago.
Bedfordshire, Cambridgeshire and Hertfordshire Major Crime Unit declared the case a "no-body" murder investigation on Friday.
Two bungalows eight miles apart were sealed off in connection with the investigation.
The woman, who is in her 50s and from Christchurch near March, Cambridgeshire, has not been seen since late January.
