South Wales Police said specialist search teams are looking for Ms Hobbs, with searches also taking place in neighbouring police force areas.
Search continues for missing mum six months after she was last seen The search is continuing for a missing mother from Cardiff six months after she was last seen.
Detective Chief Inspector Matt Powell from South Wales Police said there were "several possible explanations" for Ms Hobbs's disappearance and he was keeping "an open mind".
Based on information officers have gathered during the investigation, police have searched a number of addresses, derelict premises, vehicles and open land areas across South Wales.
The last confirmed sighting of Charlene Hobbs was in a photograph taken on a mobile phone at a property in the Adamsdown area of the city on 24 July.