The SAG Awards also include TV categories, with Japanese historical drama Shogun picking up the gong for best ensemble and its stars, Hiroyuki Sanada and Anna Sawai, named best actor and actress.
Demi Moore continued her run of success to be named best actress for her performance in body horror The Substance, while Timothee Chalamet picked up the award for best actor for his portrayal of Bob Dylan in A Complete Unknown.
Only Murders In The Building took home the prize for best comedy ensemble, with star Martin Short named best actor in a comedy series.
Jean Smart, who had previously called for cancelling the awards shows due to the wildfires that hit LA in January, was named best actress in a comedy, for her role in Hacks.
Pic: AP/Chris Pizzello] During the ceremony, Rossellini said the film's cast wanted to send their best wishes to Pope Francis, who is being treated in hospital for pneumonia and bronchitis, and wish him "a quick recovery".