Their first single Freak Like Me scored the group their first UK No1 single and they followed suit with their next single Round, Round.
The new formation was a big hit and they had THREE top ten albums together, numerous hit singles and even sang on the Band Aid 20 single.
The Babes were hit another blow when the only original band member, Keisha, quit the group in 2009.
The group's debut single, Overload, went to number six in 2000 and was nominated for a Brit Award and they released debut album One Touch.
Siobhán Donaghy and Mutya Buena, both aged just 13, had been signed as solo artists, but decided to work together after performing at the same showcase.